Consejo Superior De Investigaciones Cientificas

Biosearch, S.a.

Natac Biotech, S.l.

Esther De La Fuente García

María Monagas Juan

María Carmen Gómez-Cordovés De La Vega

Juan Francisco Espinosa Parrilla

Begoña Bartolomé´Sualdea

José Carlos Quintela Fernandez

Javier Bustos Santafé

Ignacio Garrido Lafuente

Marco Pugliese

Rosa Lebrón Aguilar

Noemí Virgili Treserres

José Carlos Quintela Fernández

Pilar Mancera Aroca

Blanca Wappenhans Battestini

Alejandro Jara García-Navas

The present invention is related to a product comprising a pentacyclic triterpene of formula (I) and a hydroxytyrosol or derivatives thereof of formula (II), pharmaceutical compositions thereof and their uses as antioxidants, anti-inflammatories and neuron protectors. 

Combination of pentacyclic triterpenes and hydroxytyrosol and derivatives thereof

The present disclosure concerns phenolic extracts containing procyanidins, propelargonidins and prodelfinidins obtained from peel of the almond [(Mili.) D. A. Webb,(L.) Batsch.,(Mili.),(L.) or(L.)]. In particular, the objective is to obtain extracts rich in proanthocyanidins with type-A bonds. The preparation method disclosed comprises: (a) a maceration of plant material with organic solvents at 25-100&#xb0; C., (b) purification by liquid-liquid extraction and/or adsorption or ion exchange chromatography, and (c) optionally, a final drying. Also disclosed are the possible activities/properties of these extracts such as anti-oxidant activity and others, which determine the use thereof as a nutritional or health ingredient, and the use thereof in the cosmetic and pharmaceutical industry.

Phenolic extracts of almond peel containing procyanidins, propelargonidins, and prodelphinidins, and method for preparation thereof

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Madrid, Spain

Esther De La Fuente García