Rohm Gmbh

Rohm Gmbh Chemische Fabrik

Roehm Gmbh Chemische Fabrik

Dieter Kramer

Horst Pennewiss

Hermann Plainer

Reiner Schnee

Waldemar Schleier

Fridolin Loffler

Volker Kasche

Gerd Janowski

Klaus Sauber

An enzyme is purified by absorbing enzymes in an aqueous solution on a specific carrier material T-PbA to which is covalently bound phenyl butylamine ligand groups.

Method of purification of penicillin amidase using

What are disclosed are a method for making a pearl-like crosslinked hydrophilic carrier polymer, capable of binding proteins, by the inverse pearl polymerization of a monomer phase comprising a monomer mixture of a certain composition and a diluent therefor, also of a certain composition, said diluent comprising at least two components which can be chosen in nature and amount to optimize the protein binding capacity of the polymer, and pearl-like hydrophilic carrier polymers made by this method.

Hydrophilic polymer carrier for proteins

Stabilized carrier-bound protein is prepared by reacting a protein in aqueous solution with a mercapto group free, water insoluble carrier which contains binding groups which are reactive with the said protein and reacting the resultant protein-containing mercapto group-free carrier with hydrogen sulfide or with a compound having a molecular weight of less than 5000, and which contains at least two mercapto groups, or at least one mercapto group and at least one hydroxy- group or primary or secondary amino group.

Preparation of stabilized carrier-bound proteins

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Mainz, Germany

Dieter Kramer