Nestec S.a.

Societe Des Produits Nestle S.a.

Institut De La Research Agronomique

Institut National De La Recherche Agronomique

Institut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement

Inra

Denis Breuille

Magali Faure

Marie Noelle Horcajada

Claire Boutry

Fanny Membrez

Luc Cynober

Christophe Moinard

Stephanie Blum-Sperisen

Christian Darimont-Nicolau

Claudia Roessle

Christiane Obled

Gabrielle Ventura

Florence Rochat

Serge Andre Dominique Rezzi

Olivier Ballevre

Karine Vidal

Myriam Richelle

Marco Enrico Turini

Gayle Crozier-Willi

Francis Rose

Irene Corthesy Theulaz

Maurice Arnal

Guy Dutot

Paul André Finot

Eduardo Schiffrin

Lionel Jean Rene Bovetto

Elizabeth Offord Cavin

Simina Popa Nita

Gary Williamson

Anne Donnet-Hughes

Julio Boza

Irène Corthesy-Theulaz

Etienne Pouteau

Paul-Andre Finot

Lionel Bovetto

Laurence Donato-Capel

Michaela Hoehne

Zamzam Kabiry (Fariba) Roughead

Thomas Schweizer

Paul-André Finot

Lionel Jean René Bovetto

Stéphanie Blum-Sperisen

Véronique Jaussan

Isabelle Savary-Auzeloux

Dominique Dardevet

Richard Gannon

Daniel Ryan Moore

Didier Remond

Lydie Combaret

Isabelle Papet

Trent Stellingwerff

Eric Delpierre

Cecile Loi

Christine Charrueau

Emil Chuang

Aline Boisset Michaud

Gerard Vinyes Pares

Serge André Dominique Rezzi

Simina Florentina Popa Nita

Daniel Moore

Fabrizio Arigoni

Kevin John Acheson

Cécile Loi

Toshio Moritani

Audrey Codran-Raison

Didier Attaix

Sabine Mercier

Philippe Patureau Mirand

Roger Fielding

The present invention relates to the treatment or prevention of conditions linked to reduced muscle mass or reduced muscle protein synthesis rate. A subject matter of the invention is a composition comprising complexes of whey protein micelles and pectin for use in the treatment or prevention of a condition selected from the group consisting of sarcopenia, muscle atrophy and negative nitrogen balance. Further aspects of the invention relate to the non-therapeutic use of a composition comprising complexes of whey protein micelles and pectin and a food composition.

Complexes of whey protein micelles and pectin and body muscle protein synthesis

Compositions contain citrulline and leucine or a metabolite thereof, such as hydroxyisocaproic acid (HICA) or beta-hydroxy-beta-methylbutyrate (HMB), including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for treatment of pre-diabetes, metabolic syndrome, or diabetes.

Compositions comprising citrulline and leucine and their use in the treatment of diabetes and metabolic syndrome

A composition comprising one or more polyphenols, such as oleuropein, rutin, curcumin or quercetin, can treat or prevent sarcopenia, reduce a loss of muscle functionality (e.g. muscle strength, gait speed, etc.), increase muscle functionality, and/or improve recovery of muscle functionality after muscle atrophy. The composition can be administered to an individual who is elderly and/or frail.

Compositions and methods using a polyphenol for musculoskeletal health

The present invention relates to a method for determining the distinctive nutritional requirements of a patient with specific nutritional needs and providing a composition meeting the distinctive nutritional requirements of said patient.

Method for determining the distinctive nutritional requirements of a patient

Compositions contain citrulline and leucine or a metabolite thereof including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for the treatment of pre-diabetes, metabolic syndrome, hyperglycemia, or diabetes.

A method of treating or preventing impaired mobility in an older adult includes administering to the older adult an effective amount of a composition containing at least one ingredient for cognitive ability, at least one ingredient for muscle and/or bone quality, and at least one ingredient for joint quality and/or functionality. The older adult can be an elderly individual and/or can have a condition that is one or more of frailty, pre-frailty, sarcopenia, recovering from sarcopenia, malnutrition, at risk of malnutrition, undergoing rehabilitation, and being scheduled to undergo rehabilitation, disorders impacting mobility such as osteoporosis, osteoarthritis, pre-osteoarthritis, osteopenia, cognitive decline. In a non-limiting example of the composition, the at least one ingredient for muscle and/or bone quality and the at least one ingredient for joint quality include a protein source, omega-3 fatty acids, and a polyphenol.

Nutritional composition for treating or preventing impaired mobility

The present invention relates to a new integrated, holistic approach to empower older adults to enhance their quality of life and independence through a personalized lifestyle and nutrition program. This is achieved by measuring the physical status of the adults with respect to strength and endurance. In addition, their nutritional status is assessed. Based on those assessments recommendations are provided with respect to particular exercise programs and nutrients that support the functions bones, muscles and cartilage. These methods can be implemented as a software program and executed on computer systems.

Assessment and advice on nutrition, endurance, and strength

A composition contains curcumin and can treat or prevent sarcopenia, reduce a loss of muscle functionality (e.g. muscle strength, gait speed, etc.), increase muscle functionality, and/or improve recovery of muscle functionality after muscle atrophy. The composition can be administered to an individual who is elderly and/or frail, optionally in a composition that further includes an omega-3 fatty acid and/or a protein source.

Compositions and methods are provided that are useful in the treatment of inflammatory bowel disease (IBD) patients. The Compositions and methods are suitable in the prevention or postponement of a relapse in inflammatory bowel disease patients.

Nutritional composition useful in the treatment of IBD patients

The present disclosure relates generally to compositions that comprise citrulline and leucine or a metabolite thereof including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for the treatment of metabolic syndrome, hyperglycemia, and/or hyperinsulinemia.

A nutritional composition is used to reconstitute an optimal healthy microbiota ecosystem in humans or animals. In particular, an ingestible carrier contains specific amino acids designed to favor the growth of bacteria favorable to individuals health or for reducing the risk of developing deleterious events. In another aspect, specific amino acids are used to reconstitute an optimal healthy microbiota ecosystem in humans or animals, in particular in infants, critically ill patients, in the case of chronic diseases or any stresses impacting the gut and in elderly people.

Amino acid supplementation for a healthy microbiota ecosystem

The present invention generally relates to the field of medical nutrition. For example, the present invention provides a composition that can be used to treat, prevent and/or reverse muscle atrophy related to immobilization and its consequences. One embodiment of the present invention concerns a composition comprising a leucine and antioxidants that can be used in accelerating muscle recovery after muscle atrophy.

Accelerating muscle recovery after immobilization-induced muscle atrophy

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Lausanne, Switzerland

Denis Breuille