Sempio Foods Company

Hedgehog, Inc.

Samsung Electronics Co., Ltd.

Dae-Hee Lee

Kye Hoon Lee

Ji-Hye Kim

Atsushi Sato

Byoung-Jin Cho

Nae-Won Jang

Jong Pil Jeon

Wook-Jae Jeon

Tomomichi Kanda

Shigeto Kobori

Hyun Ah Bae

Dong Woon Cho, I

Eon Oh

Byung-Serk Hurh

Dae Eung Kim

Suk-Ju Choi

Sang Cheul Oh

Dong Woon Cho

Jeong-Ho Nho

Sung-Hwan Lim

The present invention identifies the influence of the TGFβ/Smad3/SMO molecular mechanism in cancer cells and elucidates that a high expression level of SMO is associated with the overall survival rate of cancer patients, demonstrating that SMO is a potential prognostic marker for cancer. The present invention relates to a specific epitope of SMO as an antigen and an antibody or a fragment thereof recognizing and binding specifically to the epitope. Therefore, the antibody of the present invention is expected to be useful as a therapeutic agent for SMO-related cancers.

Epitope specific to SMO protein, antibody recognizing same, and composition comprising same

Provided is a method for producing corn gluten hydrolysate comprising: (a) separating corn gluten protein by removing carbohydrate, water soluble sugars, inorganic materials and fiber material; (b) preparing corn gluten protein lysate by carrying out acid hydrolysis, enzymatic hydrolysis or natural fermentation; and (c) increasing a content of branch chain amino acid (BCAA) which is included in the hydrolysate by isolating, concentrating, precipitating, desalting and filtering the resultant corn gluten protein lysate. With improved pre-treatment and concentration processes as compared with the conventional method, the hydrolysate prepared according to the present invention is rich in amino acids and low-molecular-weight peptides. In particular, free amino acids and branched-chain amino acids (BCAA) are included in large quantity.

Method for producing corn gluten hydrolysate and corn gluten hydrolysate using the same

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Gyeonggi-do, South Korea

Dae-Hee Lee