Nestec S.a.

Institut De La Research Agronomique

Societe Des Produits Nestle S.a.

Claudia Roessle

Florence Rochat

Denis Breuille

Marco Enrico Turini

Jalil Benyacoub

Norman Alan Greenberg

Myriam Richelle

Jennifer Rae Mager

Zamzam (Fariba) Roughead

Gayle Crozier-Willi

Julie Ann Swanson

Douglas Richard Bolster

Eduardo Schiffrin

Olivier Ballevre

Stephanie Blum-Sperisen

Cristina Cruz-Hernandez

Magali Faure

Elizabeth Offord Cavin

Michel Bourguignon

Lada Frolova

Anne Donnet-Hughes

Luc Cynober

Paul André Finot

Guy Dutot

Julio Boza

Veronique Jaussan

Zamzam Fariba Roughead

Clara Lucia Garcia Rodenas

Thomas Schweizer

Christiane Obled

Paul-André Finot

Michael Jedwab

Christina Ammann

Stéphanie Blum-Sperisen

Denis Breuillé

Véronique Jaussan

Roger Fielding

Hervé Le-Henand

Herbert Lochs

Francois Murbach

Herve Le-Henand

Agathe Raynaud-Simon

Denis Breuill

François Murbach

Alain Burde

In an embodiment, compositions comprising monoacylglycerols (MAG), such as sn-1 MAG, are administered with a lipase inhibitor, such as tetrahydrolipstatin, and/or with a diet low in fat and/or calories. In another embodiment, compositions comprising MAG, such as sn-1 MAG, are administered concurrently with a lipase inhibitor, such as tetrahydrolipstatin, and/or with fat-soluble nutrients. The compositions and the methods of using the compositions enhance absorption of fatty acids and fat-soluble nutrients such as fat-soluble vitamins and carotenoids to address nutritional deficiencies due to a weight loss diet used in association with a lipase inhibitor.

Monoacylglycerols for use in conjunction with a lipase inhibitor and/or diets low in fat and/or calories

Nutritional compositions are provided that comprise a fructo-oligosaccharaide (FOS) in an amount of 35 to 44% by weight; a polysaccharide that is not a partially hydrolyzed guar gum such as, for example, an arabinogalactan in an amount of 50% to 38% by weight; and inulin in an amount of 12% to 24% by weight. The FOS and the polysaccharide may be present in a weight ratio of about 1:1. More specifically, the FOS and inulin may be present in a weight ratio of about 7:3. Also provided are methods of promoting gut micro biota balance and health. The methods include administering an effective amount of the nutritional composition to patients in need of same.

Nutritional composition for promoting gut microbiota balance and health

In an embodiment, compositions comprising monoacylglycerols (MAG), such as sn-1(3) MAG, are administered with a lipase inhibitor, such as tetrahydrolipstatin, and/or with a diet low in fat and/or calories. In another embodiment, compositions comprising MAG, such as sn-1(3) MAG, are administered concurrently with a lipase inhibitor, such as tetrahydrolipstatin, and/or with fat-soluble nutrients. The compositions and the methods of using the compositions enhance absorption of fatty acids and fat-soluble nutrients such as fat-soluble vitamins and carotenoids to address nutritional deficiencies due to a weight loss diet used in association with a lipase inhibitor.

The invention provides a composition and method for providing nutritional support to obese patients. The composition has an energy density between 0.4 and 0.9 kcal/ml and comprises a protein source which comprises at least 30% by weight whey protein and provides at least 30% of the total calories of the composition. The composition may include a carbohydrate source and a lipid source. Preferably at least 50% by weight of the protein source is whey protein. The invention further extends to use of the composition in the prevention of treatment of malnutrition in obese patients.

Nutrition for obese patients

The present disclosure relates to nutritional compositions comprising a fructo-oligosaccharide (FOS) in an amount of 35 to 44% by weight; a polysaccharide that is not a partially hydrolyzed guar gum such as, for example, an arabinogalactan in an amount of 50% to 38% by weight; and inulin in an amount of 12% to 24% by weight. The FOS and the polysaccharide may be present in a weight ratio of about 1:1. More specifically, the FOS and inulin may be present in a weight ratio of about 7:3. Also provided are methods of promoting gut microbiota balance and health. The methods include administering an effective amount of the nutritional composition to patients in need of same.

Methods for promoting gut microbiota balance

The present invention relates to a nutritional composition which is liquid and shelf-stable or powdered and reconstitutable. The composition has a fiber content of more than 2.5 g/fibber per 100 ml of the composition. Furthermore, it has an energy content of 1.3-1.8 kcal/ml. The composition is useful to improve and maintain gut comfort, restoring a well-balanced gut flora, especially in an elderly patient prone to malnutrition. The invention further relates to a process for preparing the nutritional composition.

High fibre high calorie liquid or powdered nutritional composition

The present invention relates to a method for preparing an enteral nutrition at the bed of a patient, which involves the use of a standard enteral solution to which is added, via a closed system, one or more compositions in module form, containing selected nutrients, adapted for a specific clinical condition. The present invention also pertains to the different modules, that are preferably in dry form and to the use thereof in the treatment and/or nourishment of a critically ill person.

Nutritional modules

A composition for use as a medicament, functional food or nutritional product is described which comprises at least one lipid wherein the lipid provides greater than 35% total energy of the composition. A preferred embodiment comprises a n-6/n-3 fatty acid ratio of about 2/1 to 7/1. In addition, a method of preparing the composition; use of the composition in the manufacture of a medicament, functional food or nutritional product; and a method of treatment or treatment or prevention of sepsis or inflammatory shock which comprises administering an effective amount of the composition are described.

High lipid diet

The present invention relates to a nutritional composition suitable for patients undergoing chemotherapy and/or radiation such as cancer patients. The composition, which may be in powder or liquid form, comprises casein and whey proteins, TGF-&#x3b2; and free glutamine.

Nutritional composition against side effects of chemotherapy or radiotherapy

A composition for use as a medicament or nutritional product is described which comprises at least one lipid wherein the lipid provides greater tan 35% total energy of the composition. A prefered embodiment comprises a n-6/n-3 fatty acid ratio of about 2/1 to 7/1. In addition, a method of preparing the composition; use of the composition in the manufacture of a medicament or nutritional product; and a method of treatment or prevention of sepsis or inflammatory shock which comprises administering an effective amount of the composition are described.

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Morges, Switzerland

Claudia Roessle