Qiagen Gaithersburg Inc.

Westrock Shared Services, LLC

Smurfit-stone Container Enterprises, Inc.

Rock-tenn Shared Services, LLC

Qiagen Gaithresburg, Inc

Brian Lowe

Irina A Nazarenko

Benjamin D Strong

Attila T Lorincz

Paul Eder

Richard Mallonee

Ha Thai

Anna K Fulbright

Thomas Rothmann

Arvind Virmani

Benjamin Strong

Dominic O'Neil

Shiuli Agarwal

Holly Basham

Szymon Rus

Anna Fulbright

Irina Nazarenko

A machine for forming a container from a blank of sheet material includes an outer body frame, a mandrel mounted to the body frame, a lifting assembly coupled to the body frame, and a lateral presser assembly and a folding arm assembly coupled to the lifting assembly, wherein the lifting assembly moves the lateral presser assembly and the folding arm assembly in a first direction and an opposite, second direction. A folding arm servomechanism is operatively connected to a folding arm of the folding arm assembly and rotates the folding arm relative to the mandrel to wrap a first portion of the blank around the mandrel. A lateral presser servomechanism is operatively connected to an engaging bar of the lateral presser assembly and rotates the engaging bar relative to the mandrel to wrap a second portion of the blank around the mandrel to at least partially form the container.

Machine and method for forming a container

A barrel formed from a sheet of blank material includes a plurality of side wall panels for forming sides of the barrel including a front panel, a rear panel, two opposing end panels, and at least one diagonal corner panel, at least one bottom flap for forming a bottom of the barrel, and a plurality of top flaps for forming a top of the barrel including a top front flap foldably connected to the front panel, a top rear flap foldably connected to the rear panel, and two opposing top end flaps each foldably connected to one of the end panels. The top front flap and the top rear flap include at least one closure slot. Each of the two opposing top end flaps includes at least one locking finger. The locking fingers are inserted within the closure slots for securing the top of the barrel in a closed position.

Blank and machine for forming a container

Provided are nucleic acids capable of hybridizing to HPV 16 and/or HPV 18 nucleic acids, in particular, mRNA encoding E2 and E6-7 gene products. Such nucleic acids are useful in methods of isolating RNA from a biological sample, methods and means for determining the presence of particular RNA splice-form variants in a biological sample, methods and means for determining the relative ratio of RNA ratios in a biological sample, methods and means for predicting the progression of precancerous cervical lesions, and methods and means for detecting disruption of genes or gene expression.

Materials and methods for detection of HPV nucleic acids

Provided are methods of isolating RNA from a biological sample, methods and means for determining the presence of particular RNA splice-form variants in a biological sample, methods and means for determining the relative ratio of RNA ratios in a biological sample, and methods and means for predicting the progression of precancerous cervical lesions.

Non-target amplification method for detection of RNA splice-forms in a sample

The present disclosure relates to immobilization of a cell using a carboxylated surface by contacting the carboxylated surface with a sample comprising the cell for a sufficient time to permit the cell to bind to the carboxylated surface. The immobilized cell may then be separated from the remainder of the sample and further manipulated to isolate, concentrate, and/or analyze the cell or a component thereof.

Materials and method for immobilizing, isolating, and concentrating cells using carboxylated surfaces

Machine for forming a container

Methods and materials for determining the presence of at least one nucleic acid in a sample are provided, said methods comprising (1) a purification step using sequence specific hybrid capture; (2) an amplification step; and (3) a detection step comprising contacting the target nucleic acid with a plurality of detectably labeled nucleic acid detection probes, wherein each (a) bears a different detectable label from the other detection probes, and/or (b) has a different melting temperature from probes bearing the same detectable label. Also disclosed are compositions and kits for use in such a method.

Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids

Target-specific hybrid capture (TSHC) provides a nucleic acid detection method that is not only rapid and sensitive, but is also highly specific and capable of discriminating highly homologous nucleic acid target sequences. The method produces DNA:RNA hybrids which can be detected by a variety of methods.

Detection of nucleic acids by target-specific hybrid capture method

Container having interlocking top flaps and blanks for forming same

Apparatus for forming a barrel from a blank

A machine for forming a case from a blank of sheet material includes a body, a mandrel mounted on the body and having an external shape complimentary to an internal shape of at least a portion of the case, a member mounted on the body adjacent the mandrel for applying a force to the blank for at least one of folding a portion of the blank around the mandrel, moving the blank, and securing portions of the blank together, and a servomechanism operatively connected to the member for driving and controlling movement of the member to apply the force to the blank.

Blank and methods and apparatus for forming a dispenser case from the blank

Growing community of inventors

Olney, MD, United States of America

Brian Lowe