Cargill Inc.

Andrew Keith Ohmes

Troy Allen Rhonemus

Christopher Austin Tyler

Allan S Myerson

John J Hahn

Aron Broman Erickson

Ting Liu Carlson

John Joseph Hahn

Aron Erickson

Jeffrey C Evans

Ronny Leontina Marcel Vercauteren

Robert J Brower, Iii

Kern M Storo

An Amanda Jules Heylen

Alexander Patist

Jenna Stangler

Bruce Michael Furlano

Jenna Helgeson

Tougeu Vang

Chen-Chou Chiang

Robert Joshua Brower Iii

The invention relates to the use of adsorb/desorb chromatography to prepare enriched compositions comprising rebaudioside B and/or rebaudioside D. Compositions with enriched rebaudioside-B and/or rebaudioside-D components may be prepared from-derived glycoside compositions using an adsorb-desorb chromatography process where the stationary phase of the chromatography bed comprises a macroporous neutral adsorbent resin.

Method for the enrichment of rebaudioside b and/or rebaudioside d in stevia-derived glycoside compositions using adsorb-desorb chromatography with a macroporous neutral adsorbent resin

A process for production of crystalline rebaudioside B from rebaudioside A is described. Additionally, four distinct crystal polymorphic forms of rebaudioside B are described, as well as methods for converting from one crystal polymorphic form of rebaudioside B to another crystal polymorphic form of rebaudioside B.

Crystalline forms of rebaudioside B

The present invention provides methods to treat mixtures containing natural rebaudioside A (Reb A), rebaudioside B (Reb B), and rebaudioside D (Reb D), synthetic counterparts of these, and/or derivatives of the natural or synthetic embodiments obtain one or more of these glycosides in more pure form. In many embodiments, the invention can be used to process glycoside mixtures obtained at least in part from natural sources such as theplant. This allows, for instance, the recovery of a product including Reb A material in more pure form relative to Reb B material or Reb D material. As an alternative or in addition to recovery of the purified Reb A material, a product including Reb B material and/or Reb D material in more pure form relative to Reb A material can be obtained.

Methods to treat mixtures of glycosides to obtain one or more of these glycosides in more pure form

Disclosed are methods for the chromatographic separation of rebaudioside A from stevioside in glycoside solutions that are derived from stevia. The chromatographic separation may be an adsorb/desorb type of chromatographic separation or a fractionation type of chromatographic separation.

Separation of rebaudioside A from stevia glycosides using chromatography

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Jordan, MN, United States of America

Andrew Keith Ohmes