Danisco A/s

Max-Planck-Gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Dupont Nutrition Biosciences Aps

Direvo Biotechnology Ag

Direvo Biotech Ag

Bayer Pharma Aktiengesellschaft

Clariant Produkte Gmbh

Andre Koltermann

Ulrich Kettling

Andrei Miasnikov

Birgitta Leuthner

Oliver Kensch

Vijay Kumar

Klaus Pellangahr

Christian Votsmeier

Christoph Reisinger

Ulrich Haupts

Andreas Scheidig

Andreas Kohl

Klaus Pellengahr

Petra Schwille

Mathias Scharte

Peter Jomo Walla

Katrin Heinze

Markus Rarbach

Olafur Hedinn Fridjonsson

Christian Voetsmeier

The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding tophytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.

Mutant citrobacter freundii phytase polypeptide

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The present invention relates to enzymes and processes. In particular, there is described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme and variants thereof.

Enzymes

A method of fluorescence measurement on analytes, marked with different fluorescent markers, which have spectrally different fluorescence emissions, in a sample is described, having the following steps: illumination of the sample in the measurement volume using a laser to excite the fluorescence emission of the at least two fluorescent markers, the illumination of the measurement volume being performed with a maximum of one single laser line, having an excitation intensity sufficiently high that the fluorescent markers are jointly excited through 2-photon absorptions, detection of the fluorescence emission using at least two detector devices which are designed for light detection in different spectral ranges in accordance with the spectral fluorescence properties of the fluorescent markers, and performance of a cross-correlation and/or coincidence analysis of detector signals of the detector devices. A measurement device for performing the method is also described.

Method and device for multicolour 2-photon fluorescence coincidence analysis

The present invention provides engineered enzymes generated from protein scaffolds combined with Specificity Determining Regions, the production thereof and the use of said engineered enzymes for research, nutritional care, personal care and industrial purposes.

Engineered enzymes and uses thereof

A method for analyzing properties of a sample by measuring fluorescence parameters in multiple foci, comprises the steps of splitting a collimated primary laser beam with a splitting device into at least two collimated secondary laser beams and deflecting the secondary laser beams such that they propagate at different propagation angles with respect to an optical axis of a focussing optic, focussing the secondary laser beams with the focussing optic into at least two volume elements in the sample, detecting light emitted from the volume elements with a detecting device, and evaluating the detected light for obtaining the properties to be analyzed. Furthermore, a device for implementing this method is described. The invention is particularly suited for high-throughput screening applications.

Multi-parameter fluorimetric analysis in a massively parallel multi-focal arrangement and the use thereof

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Kö'ln, Germany

Andre Koltermann