Senomyx, Inc.

Eisai Inc.

Firmenich Incorporated

Mgi Gp, Inc.

Eisai Corporation of North America

Amy Xing

David Mark Wallace

Xiaodong Li

Mark Zoller

Catherine Tachdjian

Vincent Jacob Kalish

Jia-He Li

Jie Zhang

Guy Servant

Vincent Darmohusodo

Qing Chen

Andrew P Patron

Xiao-Qing Tang

Farid Bakir

Weizheng Xu

Sara L Adamski-Werner

Marketa Rinnova

Ming Qi

Qun Liu

Daniel Harry Rogers

Stephen Terrence Hobson

Klaus Gubernator

Ming Cai Lun Lu Qi

The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the 'umami' taste of monosodium glutamate) or sweet taste modifiers, savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.

Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof

The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the 'umami' taste of monosodium glutamate) or sweet taste modifiers,&#x2014;savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.

The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the 'umami' taste of monosodium glutamate) or sweet taste modifiers, &#x2014;savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.

The present invention provides compounds which inhibit poly(ADP-ribose) polymerase ('PARP'), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.

Compounds, methods and pharmaceutical compositions for inhibiting PARP

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San Diego, CA, United States of America

Amy Xing