Jürgen Distler

Title: Jürgen Distler: Innovator in DNA Analysis

Introduction

Jürgen Distler is a prominent inventor based in Berlin, Germany. He has made significant contributions to the field of molecular biology, particularly in the analysis of DNA methylation. With a total of 3 patents, his work has implications for cancer diagnosis and treatment.

Latest Patents

One of his latest patents is a method for the detection of cytosine methylations in DNA. This innovative technique involves converting non-methylated cytosines into uracil while leaving 5-methylcytosine unchanged. The DNA is then amplified using a polymerase and specific primers, allowing for the detection of hybridization states through various detection systems. This method is particularly useful for diagnosing and predicting cancer and other diseases linked to methylation changes.

Another notable patent is for the simultaneous amplification of multiple sequences in a PCR reaction. This method enhances the efficiency of nucleic acid amplification by using primer oligonucleotides with dual domains. The amplification process is followed by hybridization with a labeled primer, enabling detailed investigation of the amplified sequences.

Career Highlights

Jürgen Distler has established himself as a key figure in the biotechnology sector. He is currently associated with Epigenomics AG, a company focused on developing innovative diagnostic solutions. His work has not only advanced scientific understanding but also paved the way for practical applications in medicine.

Collaborations

Throughout his career, Jürgen has collaborated with notable colleagues, including Reimo Tetzner and Kurt Berlin. These partnerships have fostered a collaborative environment that enhances research and innovation in the field.

Conclusion

Jürgen Distler's contributions to DNA analysis and his innovative patents highlight his role as a leading inventor in biotechnology. His work continues to influence the landscape of molecular diagnostics and cancer research.