The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Jun. 16, 2023
Applicant:

Pliant Therapeutics, Inc., South San Francisco, CA (US);

Inventors:

David John Morgans, Jr., Los Altos, CA (US);

Randall L Halcomb, Foster City, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Hui Li, Santa Clara, CA (US);

Lan Jiang, Foster City, CA (US);

Jacob Cha, San Bruno, CA (US);

Timothy Hom, Sunnyvale, CA (US);

Assignee:

Pliant Therapeutics, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

The invention relates to compounds of formula (I): formula (I) or a salt thereof wherein R, R, R, R, X, m, n, p and q are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating tissue specific fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).


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