The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Jan. 05, 2022
Applicant:

Meharry Medical College, Nashville, TN (US);

Inventors:

Donald J. Alcendor, Hermitage, TN (US);

Waldemar Popik, Brentwood, TN (US);

Assignee:

Meharry Medical College, Nashville, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 47/59 (2017.01); A61P 31/14 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1131 (2013.01); A61K 47/593 (2017.08); A61K 47/595 (2017.08); A61P 31/14 (2018.01); C07F 9/65583 (2013.01); C12N 2310/11 (2013.01); C12N 2310/314 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/346 (2013.01); C12N 2310/351 (2013.01); C12N 2320/32 (2013.01);
Abstract

An antiviral agent is provided, having a phosphorodiamidate morpholino oligomer with an antisense sequence to a portion of a genome of a strain of Zika virus (ZIKV). The antiviral agent finds many uses, such as in a pharmaceutical composition, a method of treating ZIKV-mediated disease, a method of preventing ZIKV-mediated disease, a method of reducing or preventing the replication of ZIKV in a host cell, a method of controlling the spread of ZIKV in donated tissue, a treated tissue sample, and in the manufacture of a medicament for the treatment or prevention or ZIKV-mediated disease.


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