The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2024

Filed:

May. 06, 2021
Applicant:

Trustees of Boston University, Boston, MA (US);

Inventors:

Edward R. Damiano, Acton, MA (US);

Firas H. El-Khatib, Allston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 5/172 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61M 5/142 (2006.01); A61M 5/168 (2006.01); G16H 15/00 (2018.01); G16H 20/17 (2018.01);
U.S. Cl.
CPC ...
A61M 5/1723 (2013.01); A61B 5/14532 (2013.01); A61B 5/4839 (2013.01); A61M 5/16827 (2013.01); G16H 15/00 (2018.01); G16H 20/17 (2018.01); A61M 2005/14208 (2013.01); A61M 2005/14296 (2013.01); A61M 2202/0486 (2013.01); A61M 2202/07 (2013.01); A61M 2205/3584 (2013.01); A61M 2205/50 (2013.01); A61M 2205/502 (2013.01); A61M 2230/005 (2013.01); A61M 2230/201 (2013.01);
Abstract

Apparatus and methods calculate and deliver doses of insulin and optionally glucagon into a subject. Online operation controls delivery of correction doses of insulin automatically in response to regular glucose measurements from a sensor, and offline operation calculates and delivers correction doses based on isolated glucose measurements and information gathered autonomously during preceding online operation. In another aspect, offline operation includes automatically calculating and administering meal doses based on information gathered autonomously during preceding periods of online operation. Both methods include generating relevant control parameters tailored to the individual and continually converged upon and potentially modulated during online operation. The control parameters are employed in real time during periods of offline operation to regulate glucose level without the need for user-provided control parameters such as correction factors and insulin-to-carbohydrate ratios.


Find Patent Forward Citations

Loading…