The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2024

Filed:

Mar. 07, 2022
Applicant:

Apogee Biotechnology Corporation, Hummelstown, PA (US);

Inventors:

Charles D. Smith, Hershey, PA (US);

Kevin J. French, Harrisburg, PA (US);

Yan Zhuang, Hershey, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 61/39 (2006.01); C07C 49/323 (2006.01); C07C 49/563 (2006.01); C07C 49/567 (2006.01); C07C 49/573 (2006.01); C07C 61/40 (2006.01); C07C 69/738 (2006.01); C07C 211/27 (2006.01); C07C 211/29 (2006.01); C07C 211/48 (2006.01); C07C 211/52 (2006.01); C07C 215/76 (2006.01); C07C 217/58 (2006.01); C07C 217/60 (2006.01); C07C 233/49 (2006.01); C07C 233/59 (2006.01); C07C 233/60 (2006.01); C07C 233/62 (2006.01); C07C 255/44 (2006.01); C07C 255/56 (2006.01); C07C 275/30 (2006.01); C07C 317/32 (2006.01); C07C 323/40 (2006.01); C07D 207/09 (2006.01); C07D 207/27 (2006.01); C07D 209/08 (2006.01); C07D 209/86 (2006.01); C07D 209/88 (2006.01); C07D 211/58 (2006.01); C07D 213/38 (2006.01); C07D 213/40 (2006.01); C07D 213/89 (2006.01); C07D 233/24 (2006.01); C07D 233/64 (2006.01); C07D 257/04 (2006.01); C07D 263/58 (2006.01); C07D 277/42 (2006.01); C07D 277/46 (2006.01); C07D 277/82 (2006.01); C07D 295/027 (2006.01); C07D 295/13 (2006.01); C07D 295/30 (2006.01); C07D 317/58 (2006.01); C07D 333/20 (2006.01); C07D 333/22 (2006.01); C07D 333/28 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07C 61/39 (2013.01); C07C 49/323 (2013.01); C07C 49/563 (2013.01); C07C 49/567 (2013.01); C07C 49/573 (2013.01); C07C 61/40 (2013.01); C07C 69/738 (2013.01); C07C 211/27 (2013.01); C07C 211/29 (2013.01); C07C 211/48 (2013.01); C07C 211/52 (2013.01); C07C 215/76 (2013.01); C07C 217/58 (2013.01); C07C 217/60 (2013.01); C07C 233/49 (2013.01); C07C 233/59 (2013.01); C07C 233/60 (2013.01); C07C 233/62 (2013.01); C07C 255/44 (2013.01); C07C 255/56 (2013.01); C07C 275/30 (2013.01); C07C 317/32 (2013.01); C07C 323/40 (2013.01); C07D 207/09 (2013.01); C07D 207/27 (2013.01); C07D 209/08 (2013.01); C07D 209/86 (2013.01); C07D 209/88 (2013.01); C07D 211/58 (2013.01); C07D 213/38 (2013.01); C07D 213/40 (2013.01); C07D 213/89 (2013.01); C07D 233/24 (2013.01); C07D 233/64 (2013.01); C07D 257/04 (2013.01); C07D 263/58 (2013.01); C07D 277/42 (2013.01); C07D 277/46 (2013.01); C07D 277/82 (2013.01); C07D 295/027 (2013.01); C07D 295/13 (2013.01); C07D 295/30 (2013.01); C07D 317/58 (2013.01); C07D 333/20 (2013.01); C07D 333/22 (2013.01); C07D 333/28 (2013.01); C07D 487/04 (2013.01); C07C 2601/02 (2017.05); C07C 2603/74 (2017.05);
Abstract

The invention relates to substituted adamantane compounds, pharmaceutical compositions thereof, processes for their preparation, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease.


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