The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2022

Filed:

Feb. 21, 2019
Applicant:

Celgene Corporation, Summit, NJ (US);

Inventor:

Jerome B. Zeldis, Princeton, NJ (US);

Assignee:

Celgene Corporation, Summit, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4035 (2005.12); A61K 31/425 (2005.12); A61K 31/445 (2005.12); A61K 31/454 (2005.12); C07K 14/47 (2005.12); C07K 14/705 (2005.12); C07K 14/82 (2005.12); C07K 16/28 (2005.12); C12Q 1/6816 (2017.12); C12Q 1/6883 (2017.12); C12Q 1/6886 (2017.12); G01N 33/50 (2005.12); G01N 33/53 (2005.12); G01N 33/574 (2005.12); A61K 38/00 (2005.12);
U.S. Cl.
CPC ...
C07K 14/47 (2012.12); C07K 14/4748 (2012.12); C07K 14/705 (2012.12); C07K 14/82 (2012.12); C07K 16/28 (2012.12); C12Q 1/6816 (2012.12); C12Q 1/6883 (2012.12); C12Q 1/6886 (2012.12); G01N 33/5082 (2012.12); G01N 33/5308 (2012.12); G01N 33/574 (2012.12); G01N 33/57419 (2012.12); G01N 33/57423 (2012.12); G01N 33/57434 (2012.12); G01N 33/57484 (2012.12); G01N 33/57488 (2012.12); G01N 33/57492 (2012.12); A01K 2217/075 (2012.12); A01K 2227/105 (2012.12); A61K 38/00 (2012.12); C07K 2319/30 (2012.12); C12Q 2600/136 (2012.12); C12Q 2600/158 (2012.12); G01N 2500/00 (2012.12);
Abstract

Methods of treating, preventing and/or managing cancer as well as and diseases and disorder associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.


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