The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US RE48856 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 20, 2021

Filed:

Oct. 09, 2019
Applicants:

Vib Vzw, Ghent, BE;

Katholieke Universiteit Leuven, K.u.leuven R&d, Leuven, BE;

Inventors:

Jean-Christophe Marine, Linden, BE;

Laura Standaert, Zottegem, BE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2009.12); C07H 21/02 (2005.12); C07H 21/04 (2005.12); A61K 31/7088 (2005.12); A61K 31/713 (2005.12); A61K 45/06 (2005.12);
U.S. Cl.
CPC ...
C12N 15/113 (2012.12); A61K 31/7088 (2012.12); A61K 31/713 (2012.12); A61K 45/06 (2012.12); C12N 2310/113 (2012.12); C12N 2310/14 (2012.12); C12N 2310/3231 (2012.12); C12N 2310/341 (2012.12); C12N 2320/31 (2012.12);
Abstract

The application relates to the field of cancer, particularly to the field of solid tumors. It was found that a particular long non-coding RNA (lncRNA), NEAT1, an essential architectural component of nuclear paraspeckles, is required for the survival of cancer, but not that of normal, non-transformed, cells. Inhibition of NEAT1 reduces cell viability of cancer cells and induces apoptosis. These data identify NEAT1 as a novel therapeutic target for treatment of solid tumors.


Find Patent Forward Citations

Marine, Jean-Christophe. (2021). Inhibition of neat1 for treatment of solid tumors (U.S. Patent No. RE48856). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/RE48856

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