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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US RE48558 B1

PDFFull Text
Date of Patent:
May. 17, 2021

Filed:

Feb. 27, 2018

Anti-cd79b antibodies and immunoconjugates and methods of use

Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Yvonne Chen, San Mateo, CA (US);

Mark Dennis, San Carlos, CA (US);

David Dornan, San Mateo, CA (US);

Kristi Elkins, San Francisco, CA (US);

Jagath Reddy Junutula, Fremont, CA (US);

Andrew Polson, San Francisco, CA (US);

Bing Zheng, Mountain View, CA (US);

Assignee:

GENENTECH, INC., South San Francisco, CA (US);

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Padmashri Ponnaluri

Int. Cl.
CPC ...
A61K 51/00 (2005.12); A61K 39/44 (2005.12); C07K 19/00 (2005.12); C07K 16/28 (2005.12); A61K 47/68 (2016.12); A61K 31/537 (2005.12); A61K 38/05 (2005.12); A61K 39/395 (2005.12); A61K 45/06 (2005.12); A61K 51/10 (2005.12); C07K 16/30 (2005.12); G01N 33/574 (2005.12); A61K 39/00 (2005.12);
U.S. Cl.
CPC ...
C07K 16/2803 (2012.12); A61K 31/537 (2012.12); A61K 38/05 (2012.12); A61K 39/3955 (2012.12); A61K 39/39558 (2012.12); A61K 45/06 (2012.12); A61K 47/6803 (2017.07); A61K 47/6811 (2017.07); A61K 47/6849 (2017.07); A61K 47/6867 (2017.07); A61K 51/1027 (2012.12); C07K 16/2896 (2012.12); C07K 16/3061 (2012.12); G01N 33/57492 (2012.12); A61K 2039/505 (2012.12); C07K 2317/24 (2012.12); C07K 2317/34 (2012.12); C07K 2317/40 (2012.12); C07K 2317/55 (2012.12); C07K 2317/56 (2012.12); C07K 2317/565 (2012.12); C07K 2317/567 (2012.12); C07K 2317/73 (2012.12); C07K 2317/92 (2012.12); Y02A 50/30 (2017.12);
Abstract

The present invention is directed to compositions of matter comprising immunoconjugates comprising an anti-CD79b antibody comprising: (i) an HVR-L1 sequence of KASQSVDYEGDSFLN (SEQ ID NO: 194), (ii) an HVR-L2 sequence of AASNLES (SEQ ID NO: 195), (iii) an HVR-L3 sequence of QQSNEDPLT (SEQ ID NO: 196), (iv) an HVR-H1 sequence of GYTFSSYWIE (SEQ ID NO: 202), (v) an HVR-H2 sequence of GEILPGGGDTNYNEIFKG (SEQ ID NO: 203), and (vi) an HVR-H3 sequence of TRRVPIRLDY (SEQ ID NO: 204) and to methods of using those compositions of matter for the treatment of hematopoietic tumor in mammals.

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