The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2020

Filed:

Dec. 18, 2018
Applicant:

Naeja-rgm Pharmaceuticals Ulc, Alberta, CA;

Inventors:

Samarendra Nath Maiti, Alberta, CA;

Dai Quoc Nguyen, Alberta, CA;

Andhe V. N. Reddy, Alberta, CA;

Judy Yip, Alberta, CA;

Chan Minh Ha, Alberta, CA;

Rong Ling, Alberta, CA;

Rudong Shan, Alberta, CA;

Madhava Reddy Madala, Alberta, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 501/56 (2005.12); A61K 31/352 (2005.12); A61K 31/423 (2005.12); A61K 31/428 (2005.12); A61K 31/546 (2005.12); A61K 31/69 (2005.12); C07D 501/04 (2005.12);
U.S. Cl.
CPC ...
C07D 501/56 (2012.12); A61K 31/352 (2012.12); A61K 31/423 (2012.12); A61K 31/428 (2012.12); A61K 31/546 (2012.12); A61K 31/69 (2012.12); C07D 501/04 (2012.12);
Abstract

Cephem compounds, pharmaceutically acceptable salts thereof, and methods of using same, wherein the compound has a bicyclic nitrogen-containing aromatic heterocyclic ring as the quaternary ammoniomethyl group at the 3-position and one or both of a terminal amidine residue (substituted or unsubstituted) attached to an aryl or a 5- or 6-membered heteroaryl group (substituted or unsubstituted) which is further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain, or a terminal guanidine residue attached to an aryl or a 5- or 6-membered heteroaryl group (substituted or unsubstituted) which is further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain.


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