The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2020

Filed:

Dec. 12, 2018
Applicant:

Zynerba Pharmaceuticals, Inc., Devon, PA (US);

Inventors:

Audra Lynn Strinchcomb, Towson, MD (US);

Stan Lee Banks, Owenton, KY (US);

Miroslaw Jerzy Golinski, La Jolla, CA (US);

Jeffrey Lynn Howard, Richmond, KY (US);

Dana Carmel Hammel, Georgetown, KY (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2005.12); A61K 45/06 (2005.12); C07C 219/04 (2005.12); A61K 31/27 (2005.12); A61K 31/265 (2005.12); A61K 31/225 (2005.12); A61K 31/222 (2005.12); C07C 271/52 (2005.12); C07C 229/16 (2005.12); C07C 229/12 (2005.12); C07C 219/16 (2005.12); A61K 9/70 (2005.12);
U.S. Cl.
CPC ...
C07C 229/12 (2012.12); A61K 9/0014 (2012.12); A61K 9/0021 (2012.12); A61K 31/222 (2012.12); A61K 31/225 (2012.12); A61K 31/265 (2012.12); A61K 31/27 (2012.12); A61K 45/06 (2012.12); C07C 219/04 (2012.12); C07C 219/16 (2012.12); C07C 229/16 (2012.12); C07C 271/52 (2012.12); A61K 9/7007 (2012.12); C07C 2601/16 (2017.04);
Abstract

Described herein arecannabidiol prodrugs used in pharmaceutical compositions as well asmicroneedle drug delivery systems comprising a pharmaceutical compositions comprising pharmaceutically active agents (e.g., cannabidiol and prodrugs of cannabidiol) and microneedle arrays suitable for local and systemic delivery of the active agent to a mammal. Also described herein are methods of using a microneedle transdermal or topical drug delivery systems comprising pharmaceutical compositions, comprising cannabidiol and prodrugs of cannabidiol, and microneedle arrays in the treatment disease, including pancreatitis and pancreatic cancer.


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