The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2019

Filed:

Dec. 20, 2016
Applicant:

Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);

Inventors:

C. Frank Bennett, Carlsbad, CA (US);

Lex M. Cowsert, New Braunfels, TX (US);

Susan M. Freier, San Diego, CA (US);

Assignee:

Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2009.12);
U.S. Cl.
CPC ...
C12N 15/113 (2012.12); C12N 15/1138 (2012.12); C12N 2310/11 (2012.12); C12N 2310/315 (2012.12); C12N 2310/321 (2012.12); C12N 2310/3231 (2012.12); C12N 2310/3341 (2012.12); C12N 2310/341 (2012.12); C12N 2310/346 (2012.12);
Abstract

Disclosed herein are antisense compounds and methods for decreasing CD40. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to CD40 include hyperproliferative disorders, graft versus host disease (GVHD), graft rejection, asthma, airway hyperresponsiveness, chronic obstructive pulmonary disease (COPD), multiple sclerosis (MS), systemic lupus erythematosus (SLE), and certain forms of arthritis.


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