The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2018
Filed:
Jul. 11, 2016
Bayer Healthcare Llc, Whippany, NJ (US);
Zhuozhi Wang, Millbrae, CA (US);
Junliang Pan, Moraga, CA (US);
Joanna Grudzinska-Goebel, Berlin, DE;
Christian Votsmeier, Cologne, DE;
Jan Tebbe, Cologne, DE;
Joerg Birkenfeld, Frankfurt am Main, DE;
Nina Wobst, Köln, DE;
Simone Brückner, Cologne, DE;
Susanne Steinig, Cologne, DE;
Peter Scholz, Kleve, DE;
Bayer HealthCare LLC, Whippany, NJ (US);
Abstract
Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) are provided. Isolated nucleic acid molecules encoding monoclonal antibodies that bind TFPI are also contemplated. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.