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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US RE46630 B1

PDFFull Text
Date of Patent:
Dec. 11, 2017

Filed:

Sep. 17, 2015

Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity

Applicant:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Inventors:

Thorsten Oost, Biberach an der Riss, DE;

Dennnis Fiegen, Biberach an der Riss, DE;

Christian Gnamm, Biberach an der Riss, DE;

Sandra Handschuh, Biberach an der Riss, DE;

Stefan Peters, Biberach an der Riss, DE;

Gerald Juergen Roth, Biberach an der Riss, DE;

Assignee:

Boehringer Ingelhelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:

Marc Began

Philip I. Datlow

Primary Examiner:

Gary Kunz

Int. Cl.
CPC ...
A61K 31/54 (2005.12); A61K 38/00 (2005.12); A61P 11/06 (2005.12); A61P 17/00 (2005.12); A61P 29/00 (2005.12); C07D 213/80 (2005.12); C07D 213/82 (2005.12); C07D 401/12 (2005.12); C07D 401/14 (2005.12); C07D 405/12 (2005.12); C07D 405/14 (2005.12); C07D 409/12 (2005.12); C07D 493/08 (2005.12); C07D 413/12 (2005.12);
U.S. Cl.
CPC ...
C07D 213/80 (2012.12); C07D 213/82 (2012.12); C07D 401/12 (2012.12); C07D 401/14 (2012.12); C07D 405/12 (2012.12); C07D 405/14 (2012.12); C07D 409/12 (2012.12); C07D 413/12 (2012.12); C07D 493/08 (2012.12);
Abstract

This invention relates to substituted 4-pyridones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other auto-immune and allergic disorders, allograft rejection, and oncological diseases.

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