The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2017

Filed:

Nov. 04, 2014
Applicant:

Hough Ear Institute, Oklahoma City, OK (US);

Inventors:

R. Kent Dyer, Jr., Edmond, OK (US);

Jack V. D. Hough, Oklahoma City, OK (US);

Assignee:

HOUGH EAR INSTITUTE, Oklahoma City, OK (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2005.12); A61K 49/00 (2005.12); A61K 38/00 (2005.12); A61K 31/56 (2005.12); A61K 31/70 (2005.12); A61K 31/235 (2005.12); A61K 31/395 (2005.12); A61F 2/00 (2005.12); A61K 41/00 (2005.12); A61K 9/50 (2005.12); A61N 2/00 (2005.12); A61K 9/00 (2005.12); A61K 9/51 (2005.12); A61N 2/06 (2005.12);
U.S. Cl.
CPC ...
A61K 41/00 (2012.12); A61K 9/0046 (2012.12); A61K 9/5094 (2012.12); A61K 9/51 (2012.12); A61N 2/002 (2012.12); A61N 2/06 (2012.12);
Abstract

Diagnosing or treating a human ear includes transporting a conjugated nanoparticle or a magnetically responsive nanoparticle into a human's middle or inner ear. Otologic nanophoresis includes electrically, magnetically or electromagnetically driving a nanoparticle through a membrane of the ear, including a tympanic membrane, a round window membrane, an oval window membrane, or a circulatory membrane. An otologic diagnostic device includes a nanoparticle conjugated with a material selected from the group consisting of lipids, proteins, growth factors, growth hormones, antioxidants, free radical scavengers, steroid preparations, and metabolically active substances; an otologic therapeutic device includes the same categories of substances and chemotherapeutic drugs. Another otologic composition includes a nanoparticle conjugated with a substance perceptible to magnetic resonance imaging.


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