The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2016

Filed:

Apr. 21, 2015
Applicant:

Teva Pharmaceuticals International Gmbh, Jona, CH;

Inventors:

Clas Sonesson, Billdal, SE;

Bengt Andersson, Göteborg, SE;

Susanna Waters, Göteborg, SE;

Nicholas Waters, Göteborg, SE;

Joakim Tedroff, Danderyd, SE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/22 (2005.12); C07D 405/00 (2005.12); C07D 211/20 (2005.12); C07D 211/32 (2005.12); C07D 405/06 (2005.12); C07D 211/34 (2005.12); C07D 211/18 (2005.12); C07D 295/155 (2005.12); C07D 211/24 (2005.12); C07D 211/70 (2005.12); C07D 211/00 (2005.12); C07D 295/073 (2005.12); C07D 295/096 (2005.12); C07D 295/112 (2005.12);
U.S. Cl.
CPC ...
C07D 295/073 (2012.12); C07D 211/18 (2012.12); C07D 211/20 (2012.12); C07D 211/22 (2012.12); C07D 211/24 (2012.12); C07D 211/32 (2012.12); C07D 211/34 (2012.12); C07D 211/70 (2012.12); C07D 295/096 (2012.12); C07D 295/112 (2012.12); C07D 295/155 (2012.12); C07D 405/06 (2012.12);
Abstract

New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)-piperidine compounds of Formula (1), wherein X N, CH, or C, however X may only be C when the compound comprises a double bond at the dotted line; Ris OSOCF, OSOCH, SOR, SOR, COR, NO, or CONHRand when X is CH or C Rmay also be CF, CN, F, Cl, Br, or I; Ris a C-Calkyl, an allyl, CHSCH, CHCHOCH, CHCHCHF, CHCF, 3,3,3-trifluoropropyl, 4,4,4,-trifluorobutyl, or —(CH)—R; Ris a C-Calkyl CF, or N(R); Ris a C-Ccycloalkyl, 2-tetrahydrofurane or 3-tetra-hydrofurane, as well as pharmaceutically acceptable salts thereof are disclosed. Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed


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