The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 23, 2015

Filed:

Nov. 08, 2012
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Shanta M. Modak, River Edge, NJ (US);

Milind S. Shintre, Karvenagar Pune, IN;

Lauserpina Caraos, Hollis, NY (US);

Trupti Gaonkar, Branchburg, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/315 (2005.12); A61Q 19/00 (2005.12); A61K 8/27 (2005.12);
U.S. Cl.
CPC ...
A61Q 19/00 (2012.12); A61K 8/27 (2012.12);
Abstract

The addition of low concentrations of combinations of water-soluble organic salts of zinc to gels, creams, lotions or ointments can increase the ability of these products to reduce or prevent exogenous irritants from causing irritation of the underlying substrate. The addition of low concentrations of combinations of water-soluble organic zinc salts to these gels, creams, lotions or ointments also can reduce the irritation of skin or mucous membranes caused by the addition of potentially-irritating substances such as spermicides, microbicides, fungicides or other therapeutic agents to the gel, cream, lotion or ointment. The advantages of this anti-irritant approach over others, which generally employ high concentrations of single zinc salts, are the reduced potential for zinc toxicity, the reduced potential for toxicity related to zinc itself, and the preservation of the desirable biological properties of potentially-irritating therapeutic substances added to the gel, cream, lotion or ointment.


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