The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2013
Filed:
Dec. 27, 2012
Kerry W. Fowler, Seattle, WA (US);
Danwen Huang, Sammamish, WA (US);
Edward A. Kesicki, Bothell, WA (US);
Hua Chee Ooi, Kirkland, WA (US);
Amy Oliver, Bothell, WA (US);
Fuqiang Ruan, Bellevue, WA (US);
Jennifer Treiberg, Redmond, WA (US);
Kamal Deep Puri, Lynnwood, WA (US);
Kerry W. Fowler, Seattle, WA (US);
Danwen Huang, Sammamish, WA (US);
Edward A. Kesicki, Bothell, WA (US);
Hua Chee Ooi, Kirkland, WA (US);
Amy Oliver, Bothell, WA (US);
Fuqiang Ruan, Bellevue, WA (US);
Jennifer Treiberg, Redmond, WA (US);
Kamal Deep Puri, Lynnwood, WA (US);
ICOS Corporation, Indianapolis, IN (US);
Abstract
The invention provides a class of substituted quinazolinone compounds and methods of treating diseases mediated by PI3Kδ activity. The disclosed compounds are useful in treating diseases such as bone-resorption disorders; and cancer, especially hematopoietic cancers, lymphomas, multiple myelomas and leukemia. The compounds are also useful in disrupting or inhibiting cellular processes such as leukocyte function or accumulation, neutrophils function, lymphocyte proliferation, and endogenous immune responses.