The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2012

Filed:

Jul. 20, 2011
Applicants:

Yvo Graus, Odijk, NL;

Jacques Himber, Guebwiller, FR;

Miranda Jansen-molenaar, Maarssen, NL;

Dorothee Kling, Kandern, DE;

Erhard Kopetzki, Penzberg, DE;

Paul Parren, Odijk, NL;

Frank Rebers, Utrecht, NL;

Beat Steiner, Dornach, CH;

Anne Stern, Penzberg, DE;

Pamela Strein, Weinheim, DE;

Kay-gunnar Stubenrauch, Penzberg, DE;

Jan Van DE Winkel, Zeist, NL;

Martine Van Vugt, Houten, NL;

Inventors:

Yvo Graus, Odijk, NL;

Jacques Himber, Guebwiller, FR;

Miranda Jansen-Molenaar, Maarssen, NL;

Dorothee Kling, Kandern, DE;

Erhard Kopetzki, Penzberg, DE;

Paul Parren, Odijk, NL;

Frank Rebers, Utrecht, NL;

Beat Steiner, Dornach, CH;

Anne Stern, Penzberg, DE;

Pamela Strein, Weinheim, DE;

Kay-Gunnar Stubenrauch, Penzberg, DE;

Jan Van de Winkel, Zeist, NL;

Martine Van Vugt, Houten, NL;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2005.12); C07K 16/28 (2005.12);
U.S. Cl.
CPC ...
Abstract

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).


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