The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2012

Filed:

Mar. 16, 2011
Applicants:

Nisar Ahmed Khan, Rotterdam, NL;

Robbert Benner, Barendrecht, NL;

Inventors:

Nisar Ahmed Khan, Rotterdam, NL;

Robbert Benner, Barendrecht, NL;

Assignee:

Biotempt B.V., Keokange, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/103 (2005.12); A61K 38/07 (2005.12);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds exhibiting immuno-regulatory activity as determined by measuring the compound's ability to modulate production of NO by a cell. Preferred compounds include or consist of a sequenceAAL AAQ AAG AAVwherein AAL is a substituted or unsubstituted non-polar amino acid selected from the group consisting of Ala and Leu; wherein AAQ is a substituted or unsubstituted amino acid selected from the group consisting of Gln, Pro, and Ala; wherein AAG is a substituted or unsubstituted amino acid Gly, and wherein AAV is a substituted or unsubstituted non-polar amino acid selected from the group consisting of Val and Ala. In one embodiment, the compound consists of a tripeptide selected from the group AQG, MTR, VVC, and mixtures thereof.


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