The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2011

Filed:

Dec. 20, 2007
Applicants:

Pascal Druzgala, Santa Rosa, CA (US);

Peter G. Milner, Los Altos Hills, CA (US);

Jurg Pfister, Los Altos, CA (US);

Cyrus Becker, Fremont, CA (US);

Inventors:

Pascal Druzgala, Santa Rosa, CA (US);

Peter G. Milner, Los Altos Hills, CA (US);

Jurg Pfister, Los Altos, CA (US);

Cyrus Becker, Fremont, CA (US);

Assignee:

ARYx Therapeutics, Inc., Fremont, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2005.12); C07D 211/56 (2005.12);
U.S. Cl.
CPC ...
Abstract

The subject invention provides novel compounds and compositions for the safe and effective treatment of gastroesophageal reflux and related conditions. In a preferred embodiment, the compositions of the subject invention comprise esterified cisapride derivatives. These compositions possess potent activity in treating gastroesophageal reflux disease and substantially reduce adverse effects associated with the administration of cisapride. These adverse effects include, but are not limited to, diarrhea, abdominal cramping and elevations of blood pressure and heart rate.


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