The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2011
Filed:
Feb. 18, 2004
Alexander Hillisch, Solingen, DE;
Olaf Peters, Tabarz, DE;
Christian Gege, Ehingen, DE;
Gerhard Siemeister, Berlin, DE;
Eberhard Unger, Cospeda, DE;
Bernd Menzenbach, Jena, DE;
Alexander Hillisch, Solingen, DE;
Olaf Peters, Tabarz, DE;
Christian Gege, Ehingen, DE;
Gerhard Siemeister, Berlin, DE;
Eberhard Unger, Cospeda, DE;
Bernd Menzenbach, Jena, DE;
Sterix Limited, Berkshire, GB;
Abstract
This invention relates to 2-substituted D-homo-estra-1,3,5(10)-trien-3-yl sulfamates of general formula I (I), in which R3 means a C1-C5-alkyl or C1-C5-alkyloxy group as well as their use for the production of a pharmaceutical agent for treating tumor diseases, which can be influenced positively by the inhibition of tubulin polymerization. The compounds according to the invention are distinguished by a D-homo-substitution. They have a special action with respect to tubulin polymerization inhibition and can be used, for example, for treating prostate cancer