The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2010

Filed:

Oct. 12, 2009
Applicants:

Todd A. Blumenkopf, Old Lyme, CT (US);

Mark E. Flanagan, Gales Ferry, CT (US);

Michael J. Munchhof, Salem, CT (US);

Inventors:

Todd A. Blumenkopf, Old Lyme, CT (US);

Mark E. Flanagan, Gales Ferry, CT (US);

Michael J. Munchhof, Salem, CT (US);

Assignee:

Pfizer Inc., Madison, NJ (US);

Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2005.12); A61K 31/519 (2005.12); A61P 11/06 (2005.12); A61P 17/06 (2005.12); A61P 19/02 (2005.12); A61P 37/06 (2005.12);
U.S. Cl.
CPC ...
Abstract

A compound of the formulawherein R, Rand Rare as defined above, which are inhibitors of the enzyme protein kinases such as Janus Kinase 3 and as such are useful therapy as immunosuppressive agents for organ transplants, xeno transplation, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, Leukemia and other autoimmune diseases.


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