The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2010
Filed:
Feb. 17, 2009
Katherine S. Bowdish, Del Mar, CA (US);
Shana Frederickson, Solana Beach, CA (US);
John Mcwhirter, Chula Vista, CA (US);
Toshiaki Maruyama, La Jolla, CA (US);
Ying-chi Lin, San Diego, CA (US);
Katherine S. Bowdish, Del Mar, CA (US);
Shana Frederickson, Solana Beach, CA (US);
John McWhirter, Chula Vista, CA (US);
Toshiaki Maruyama, La Jolla, CA (US);
Ying-Chi Lin, San Diego, CA (US);
Alexion Pharmaceuticals, Inc., Cheshire, CT (US);
Abstract
Templates that are engineered to contain a predetermined sequence and a hairpin structure are provided by a nested oligonucleotide extension reaction. The engineered template allows Single Primer Amplification (SPA) to amplify a target sequence within the engineered template. In particularly useful embodiments, the target sequences from the engineered templates are cloned into expression vehicles to provide a library of polypeptides or proteins, such as, for example, an antibody library.