The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2009
Filed:
Jan. 04, 2001
Andreas Bathe, Darmstadt, DE;
Heinz Bokel, Darmstadt, DE;
Ralf Knieriemen, Gross-Zimmern, DE;
Christoph Muermann, Dieburg, DE (US);
Thomas Keil, Münster/Altheim, DE;
Andreas Bathe, Darmstadt, DE;
Heinz Bokel, Darmstadt, DE;
Ralf Knieriemen, Gross-Zimmern, DE;
Christoph Muermann, Dieburg, DE (US);
Thomas Keil, Münster/Altheim, DE;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The invention relates to a process for the preparation of 5-arylnicotinaldehydes by reduction of the corresponding 5-arylnicotinic acids by catalytic hydrogenation in the presence of carboxylic anhydrides in which the catalyst used is a palladium/ligand complex, characterized in that the molar ratio between palladium and ligand is from 1:5 to 1:15 in the case of monodentate ligands and from 1:2.5 to 1:7.5 in the case of bidentate ligands.