The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2009

Filed:

Oct. 23, 2001
Applicants:

Bert Vogelstein, Baltimore, MD (US);

Kenneth W. Kinzler, Bel Air, MD (US);

Hans Albertsen, Cupertino, CA (US);

Rakesh Anand, Sandbach, GB;

Mary Carlson, Salt Lake City, UT (US);

Joanna Groden, Salt Lake City, UT (US);

Philip Hedge, Winsford, GB;

Geoff Joslyn, Salt Lake City, UT (US);

Alexander Fred Markham, Crewe, GB;

Yusuke Nakumura, Tokyo, JP;

Andrew Thliveris, Salt Lake City, UT (US);

Raymond White, Salt Lake City, UT (US);

Inventors:

Bert Vogelstein, Baltimore, MD (US);

Kenneth W. Kinzler, Bel Air, MD (US);

Hans Albertsen, Cupertino, CA (US);

Rakesh Anand, Sandbach, GB;

Mary Carlson, Salt Lake City, UT (US);

Joanna Groden, Salt Lake City, UT (US);

Philip Hedge, Winsford, GB;

Geoff Joslyn, Salt Lake City, UT (US);

Alexander Fred Markham, Crewe, GB;

Yusuke Nakumura, Tokyo, JP;

Andrew Thliveris, Salt Lake City, UT (US);

Raymond White, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2005.12); A61K 39/395 (2005.12);
U.S. Cl.
CPC ...
Abstract

A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. These results suggest that APC is a tumor suppressor.


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