The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2008

Filed:

Oct. 31, 2004
Applicants:

Kanti Jain, New York, NY (US);

Albert L. Rubin, Englewood, NJ (US);

Barry Smith, New York, NY (US);

Inventors:

Kanti Jain, New York, NY (US);

Albert L. Rubin, Englewood, NJ (US);

Barry Smith, New York, NY (US);

Assignee:

The Rogosin Institute, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2005.12); C12N 11/02 (2005.12); C12N 11/10 (2005.12); C12N 5/00 (2005.12); C12N 5/08 (2005.12);
U.S. Cl.
CPC ...
Abstract

Biological agents such as secretory cells are encapsulated in a hydrophilic gel made of agarose or collagen-agarose and gelatin sponge-agarose combinations. In a preferred embodiment, semi-solid beads are formed from a suspension containing collagen, agarose and secretory cells such as pancreatic islets, the collagen is polymerized to form solid, agarose-collagen beads and the solid beads are coated with agarose. Coating is preferably by rolling the solid beads in about 5-10% agarose, contacting the rolled beads with mineral oil and washing oil from the beads. Beads containing secretory cells can be transplanted into a mammal to treat a condition caused by impaired secretory cell function.


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