The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US RE40535 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 06, 2008

Filed:

May. 13, 2002
Applicants:

Fernando J. R. DO Couto, Pleasanton, CA (US);

Roberto L. Ceriani, Lafayette, CA (US);

Jerry A. Peterson, Eureka, CA (US);

Inventors:

Fernando J. R. do Couto, Pleasanton, CA (US);

Roberto L. Ceriani, Lafayette, CA (US);

Jerry A. Peterson, Eureka, CA (US);

Assignee:

IBC Pharmaceuticals, Inc., Morris Plains, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2005.12); A61K 49/00 (2005.12); C12N 5/16 (2005.12); G01N 33/53 (2005.12);
U.S. Cl.
CPC ...
Abstract

An anti-KC-4 humanized monoclonal antibody that comprises the variable regions of the light and heavy chains of the anti-KC-4 murine antibody, wherein the light chain has 7 amino acids and the heavy chain has 12 amino acids of the framework regions substituted with amino acid present in equivalent positions in antibodies of a species other than munne, and the constant regions of a human antibody. The antibody may be labeled and/or glycosylated, and is presented as a composition with a carrier. The anti-KC-4 monoclonal antibody is used in diagnostic kits for cancer and in in vivo methods of imaging and treating a primary or metastasized cancer, and in vitro diagnosis and ex vivo purging neoplastic cells from a biological fluid. RNAs and DNAs encode the monoclonal antibody, and a hybrid vector carrying the nucleotides and transfected cells express the peptides.


Find Patent Forward Citations

Couto, Fernando J. R. do. (2008). Anti-kc4 humanized monoclonal antibody and cells that express the antibody (U.S. Patent No. RE40535). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/RE40535

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