The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2007

Filed:

Jan. 12, 2004
Applicants:

Verena D. Huebner, Benicia, CA (US);

Xiaodong Lin, Hercules, CA (US);

Ian James, Rowville, AU;

Liya Chen, East Brunswick, NJ (US);

Manoj C. Desai, Pleasant Hill, CA (US);

Beata Krywult, Oakleigh East, AU;

Rajinder Singh, Belmont, CA (US);

Liang Wang, Lafayette, CA (US);

Inventors:

Verena D. Huebner, Benicia, CA (US);

Xiaodong Lin, Hercules, CA (US);

Ian James, Rowville, AU;

Liya Chen, East Brunswick, NJ (US);

Manoj C. Desai, Pleasant Hill, CA (US);

Beata Krywult, Oakleigh East, AU;

Rajinder Singh, Belmont, CA (US);

Liang Wang, Lafayette, CA (US);

Assignee:

Chiron Corporation, Emeryville, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2005.12); A61P 19/10 (2005.12); C07D 231/12 (2005.12);
U.S. Cl.
CPC ...
Abstract

Estrogen receptor-modulating pyrazole compounds are described in addition to methods and compositions for treating or preventing estrogen receptor-mediated disorders. The compounds described have been found to have unexpected and surprising activity in modulating estrogen receptor activity. Thus, the compounds of the present invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimer's disease.


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