The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2007

Filed:

Feb. 15, 2006
Applicants:

Albert J. Robichaud, Landenberg, PA (US);

Taekyu Lee, Wilmington, DE (US);

Wei Deng, Wilmington, DE (US);

Ian S. Mitchell, Philadelphia, PA (US);

Michael Guang Yang, Wilmington, DE (US);

Simon Haydar, Niskayuna, NY (US);

Wenting Chen, Exton, PA (US);

Christopher D. Mcclung, Wilmington, DE (US);

Emile J. B. Calvello, Bryn Mawr, PA (US);

David M. Zawrotny, Moorestown, NJ (US);

Parthasarathl Rajagopalan, Chennai, IN;

Inventors:

Albert J. Robichaud, Landenberg, PA (US);

Taekyu Lee, Wilmington, DE (US);

Wei Deng, Wilmington, DE (US);

Ian S. Mitchell, Philadelphia, PA (US);

Michael Guang Yang, Wilmington, DE (US);

Simon Haydar, Niskayuna, NY (US);

Wenting Chen, Exton, PA (US);

Christopher D. McClung, Wilmington, DE (US);

Emile J. B. Calvello, Bryn Mawr, PA (US);

David M. Zawrotny, Moorestown, NJ (US);

Parthasarathl Rajagopalan, Chennai, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/00 (2005.12); C07D 243/00 (2005.12); C07D 491/00 (2005.12); C07D 241/36 (2005.12); A61K 31/55 (2005.12);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to certain novel compounds represented by structural Formula (I)or pharmaceutically acceptable salt forms thereof, wherein R, R, R, R, R, R, R, X, b, k, m, and n, and the dashed lines are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep disorders, sexual disorders, migraine, conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.


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