The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2007
Filed:
Mar. 24, 2005
Michael Chorev, Jerusalem, IL;
Tamar Goren, Rehovot, IL;
Yacov Herzig, Ra'ananna, IL;
Jeffrey Sterling, Jerusalem, IL;
Marta Weinstock-rosin, Jerusalem, IL;
Moussa B. H. Youdim, Haifa, IL;
Michael Chorev, Jerusalem, IL;
Tamar Goren, Rehovot, IL;
Yacov Herzig, Ra'ananna, IL;
Jeffrey Sterling, Jerusalem, IL;
Marta Weinstock-Rosin, Jerusalem, IL;
Moussa B. H. Youdim, Haifa, IL;
Teva Pharmaceutical Industries, Ltd., Petach-Tikva, IL;
Yissum Research Development Company of the Hebrew University of Jerusalem, Jerusalem, IL;
Technion Research and Development Foundation, Ltd., Haifa, IL;
Abstract
This invention is directed to compounds of the following formula:wherein when a is 0, b is 1 or 2; when a is 1, b is 1, m is from 0-3, X is O or S, Y is halogeno, Ris hydrogen Calkyl, Ris hydrogen, Calkyl, or optionally substituted propargyl and Rand Rare each independently hydrogen, Calkyl, Caryl, Caralkyl each optionally substituted. This invention is also directed to the use of these compounds for treating depression, Attention Deficit Disorder (ADD), Attention Deficit and Hyperactivity Disorder (ADHD), Tourette's Syndrome, Alzheimer's Disease and other dementia's such as senile dementia, dementia of the Parkinson's type, vascular dementia and Lewy body dementia. This invention is further directed to a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.