The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2007
Filed:
Jun. 09, 1997
Applicant:
Shlomo Dagan, Rehovot, IL;
Inventor:
Shlomo Dagan, Rehovot, IL;
Assignee:
XTL Biopharmaceuticals Limited, Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/42 (2005.12); A61K 39/395 (2005.12);
U.S. Cl.
CPC ...
Abstract
Disclosed is a hybridoma cell line which produces human antibodies capable of binding to the hepatitis B virus surface antigen (HBVsAg), as well as antibodies produced by the cell line. Also disclosed are various uses of said antibodies in the prevention and treatment of HBV infection. Peripheral blood lymphocytes obtained from human donors having a high titer of anti HBVsAg antibodies are activated in vitro with pokeweed mitogen and then fused with heteromyeloma cells to generate hybridomas secreting human antibodies having a high affinity and specificity to HBVsAg.