The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2006
Filed:
Dec. 21, 1999
Baldomero M. Olivera, Salt Lake City, UT (US);
Jean E. F. Rivier, La Jolla, CA (US);
Lourdes J. Cruz, Salt Lake City, UT (US);
Fe Abogadie, Evanston, IL (US);
Chris E. Hopkins, Salt Lake City, UT (US);
John Dykert, Vista, CA (US);
Josep L. Torres, Barcelona, ES;
Baldomero M. Olivera, Salt Lake City, UT (US);
Jean E. F. Rivier, La Jolla, CA (US);
Lourdes J. Cruz, Salt Lake City, UT (US);
Fe Abogadie, Evanston, IL (US);
Chris E. Hopkins, Salt Lake City, UT (US);
John Dykert, Vista, CA (US);
Josep L. Torres, Barcelona, ES;
University of Utah Research Foundation, Salt Lake City, UT (US);
The Salk Institute for Biological Studies, LaJolla, CA (US);
Abstract
Substantially pure conotoxins are provided which inhibit synaptic transmissions at the neuromuscular junctions and which are useful both in vivo and in assays because they specifically target particular receptors, such as the acetyl-choline receptor, and ion channels. The peptides are of such length that they can be made by chemical synthesis. They also may be made using recombinant DNA techniques, and the DNA encoding such conotoxins having pesticidal properties can be incorporated as plant defense genes into plant species of interest.