The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2006
Filed:
May. 14, 2002
Richard Henry Jones, London, GB;
Fariba Shojaee-moradi, London, GB;
Peter Henri Sonksen, London, GB;
Dietrich Brandenburg, Reichelsheim, DE;
Achim Schuttler, Aachen, DE;
Heike Eckey, Darmstadt, DE;
Richard Henry Jones, London, GB;
Fariba Shojaee-Moradi, London, GB;
Peter Henri Sonksen, London, GB;
Dietrich Brandenburg, Reichelsheim, DE;
Achim Schuttler, Aachen, DE;
Heike Eckey, Darmstadt, DE;
BTG International Limited, London, GB;
Abstract
The invention provides an analogue of a pharmaceutical active whose molecular weight is less than 25,000 Daltons, the analogue comprising a pharmaceutical active whose molecular weight is less than 25,000 Daltons covalently linked to a pendant molecular group wherein as a result of the administration of the composition to the human or animal body an active complex having a molecular weight of 25,000 Daltons or greater is present in the human or animal circulatory system. The analogue is hepatoselective when administered to the circulatory system. Preferably the analogue is an insulin analogue comprising an insulin or functional equivalent thereof covalently linked to the pendant molecular group wherein the active complex is an insulin complex. Such an insulin analogue may be used in a method of insulin replacement therapy.