The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2005
Filed:
Nov. 13, 2002
Thomas H. Barrows, Austell, GA (US);
Terry W. Lewis, Woodbury, MN (US);
Myhanh T. Truong, Cottage Grove, MN (US);
Matthew T. Scholz, Woodbury, MN (US);
Thomas H. Barrows, Austell, GA (US);
Terry W. Lewis, Woodbury, MN (US);
Myhanh T. Truong, Cottage Grove, MN (US);
Matthew T. Scholz, Woodbury, MN (US);
3M Innovative Properties Company, St. Paul, MN (US);
Abstract
This invention is related to an adhesive composition which may be used to bond or seal tissue in vivo. The adhesive composition is readily formed from a two component mixture which includes a first part of a protein, preferably a serum albumin protein, in an aqueous buffer having a pH in the range of about 8.0-11.0 and a second part of a water-compatible or water-soluble bifunctional crosslinking agent. When the two parts of the mixture are combined, the mixture is initially a liquid which cures in vivo on the surface of tissue in less than about one minute to give a strong, flexible, pliant substantive composition which bonds to the tissue and is absorbed in about four to sixty days. The adhesive composition may be used either to bond tissue, to seal tissue or to prevent tissue adhesions caused by surgery.