The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2018

Filed:

Feb. 06, 2017
Applicant:

Pulmonx, Redwood City, CA (US);

Inventors:

Edward P. Ingenito, North Quincy, MA (US);

James A. Krom, Belmont, MA (US);

Alexander Schwarz, Brookline, MA (US);

Larry W. Tsai, Boston, MA (US);

Assignee:

Pulmonx Corporation, Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 24/06 (2006.01); C08J 9/30 (2006.01); C08J 9/36 (2006.01); C08J 3/075 (2006.01); A61L 24/00 (2006.01); C08F 116/06 (2006.01); A61M 25/10 (2013.01);
U.S. Cl.
CPC ...
A61L 24/06 (2013.01); A61L 24/0031 (2013.01); A61L 24/0036 (2013.01); A61L 24/0042 (2013.01); A61M 25/10 (2013.01); C08F 116/06 (2013.01); C08J 3/075 (2013.01); C08J 9/30 (2013.01); C08J 9/36 (2013.01); A61L 2300/604 (2013.01); A61L 2400/06 (2013.01); A61M 2025/1052 (2013.01); A61M 2210/1039 (2013.01); C08F 2810/20 (2013.01); C08J 2205/022 (2013.01); C08J 2207/10 (2013.01); C08J 2329/04 (2013.01);
Abstract

One aspect of the invention relates to a hydrogel comprising a non-natural polymer comprising a plurality of pendant nucleophilic groups and a crosslinker comprising at least two pendant electrophilic groups. Another aspect of the invention relates to a hydrogel comprising a non-natural polymer comprising a plurality of pendant electrophilic groups and a crosslinker comprising at least two pendant nucleophilic groups. Yet another aspect of the invention relates to a method for reducing lung volume in a patient comprising the step of administering a hydrogel composition as described herein. Further, hydrogels of the invention may be used to achieve pleurodesis, seal brochopleural fistulas, seal an air leak in a lung, achieve hemostasis, tissue sealing (e.g., blood vessels, internal organs), or any combination thereof. In certain embodiments, the compositions and methods described herein are intended for use in the treatment of patients with emphysema.


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