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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9999683 B1

PDFFull Text
Date of Patent:
Jun. 19, 2018

Filed:

Mar. 14, 2014

Method for identifying and treating a patient having tumor lesions comprising administering a gene therapy retroviral vector particle comprising a mutated hsv-thymidine kinase (hsv-tk) polynucleotide

Applicant:

Epeius Biotechnologies Corporation, San Marino, CA (US);

Inventors:

John P. Levy, Lake Elsinore, CA (US);

Rebecca A. Reed, Sherman Oaks, CA (US);

Joseph McNulty, Pasadena, CA (US);

Robert G. Johnson, Jr., Lafayette, CA (US);

Assignee:

EPEIUS BIOTECHNOLOGIES CORPORATION, San Marino, CA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Titilayo Moloye

Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 9/12 (2006.01); A61K 31/713 (2006.01); A61K 31/522 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
A61K 48/00 (2013.01); A61K 31/522 (2013.01); A61K 31/713 (2013.01); A61K 48/005 (2013.01); C07K 14/005 (2013.01); C12N 9/1211 (2013.01); C12Y 207/01021 (2013.01); C12N 2710/16622 (2013.01); C12N 2740/13034 (2013.01);
Abstract

Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.

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Quick Actions:

Levy, John. (2018). Method for identifying and treating a patient having tumor lesions comprising administering a gene therapy retroviral vector particle comprising a mutated hsv-thymidine kinase (hsv-tk) polynucleotide (U.S. Patent No. 9999683). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9999683

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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