The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2018

Filed:

Nov. 15, 2013
Applicant:

Utah-inha Dds & Advanced Therapeutics Research Center, Incheon, KR;

Inventors:

Se Yoon Kim, Gyeonggi-do, KR;

Don Haeng Lee, Seoul, KR;

Yixian Li, Incheon, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2017.01); A61K 9/16 (2006.01); A61K 31/136 (2006.01); A61K 31/4745 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 31/437 (2006.01); A61K 31/727 (2006.01); A61K 31/737 (2006.01); A61K 38/38 (2006.01); A61K 47/36 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 9/1652 (2013.01); A61K 9/1658 (2013.01); A61K 31/136 (2013.01); A61K 31/437 (2013.01); A61K 31/4745 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 31/727 (2013.01); A61K 31/737 (2013.01); A61K 38/385 (2013.01); A61K 47/36 (2013.01);
Abstract

The present invention relates to a biodegradable microbead having improved adsorptive power to anticancer drugs, to a method for preparing same, and to a method for treating cancer using same. According to the present invention, a rigid bead having excellent adsorptive power to anticancer drugs can be prepared through cross-linking and an amide bond between an albumin and an anionic polymer. Also, the microbead of the present invention is prepared by a biocompatible and biodegradable polymer so as to be safe when applied to the human body. Further, the microbead of the present invention can effectively inhibit the growth of a tumor by effectively blocking a blood vessel which supplies nutrients to a liver tumor, while continuously releasing anticancer drugs which are adsorbed into the surface of the bead. Thus, the present invention can be usefully applied to a chemoembolization of liver cancer.


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