The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2018

Filed:

May. 18, 2016
Applicants:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Inventors:

Jacques Galipeau, Atlanta, GA (US);

Hsiang-Chuan Hsieh, Atlanta, GA (US);

Assignees:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/19 (2006.01); A61K 39/39 (2006.01); C07K 14/535 (2006.01); C07K 14/54 (2006.01); A61K 39/00 (2006.01); A61K 35/14 (2015.01); A61K 38/20 (2006.01); A61K 39/245 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 35/14 (2013.01); A61K 38/193 (2013.01); A61K 38/2046 (2013.01); A61K 39/0005 (2013.01); A61K 39/0011 (2013.01); A61K 39/245 (2013.01); C07K 14/535 (2013.01); C07K 14/5418 (2013.01); A61K 38/00 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/55527 (2013.01); A61K 2039/572 (2013.01); C07K 2319/00 (2013.01);
Abstract

In certain embodiments, this disclosure relates to conjugates comprising GM-CSF and IL-7 and uses related thereto, e.g., enhancing the adaptive immune system. Typically the GM-CSF and IL-7 are connected by a polymer linker, e.g., polypeptide. In certain embodiments, the disclosure relates to nucleic acids encoding these polypeptide conjugates, vectors comprising nucleic acid encoding polypeptide conjugates, and protein expression systems comprising these vectors such as infectious viral particles and host cells comprising such a nucleic acids.


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