The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

Aug. 12, 2014
Applicant:

Health Research, Inc., Buffalo, NY (US);

Inventors:

Kailash Chadha, Williamsville, NY (US);

Willie Underwood, Williamsville, NY (US);

Austin Miller, Amherst, NY (US);

Assignee:

Health Research, Inc., Buffalo, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/574 (2006.01); C07K 14/54 (2006.01); C07K 14/525 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57434 (2013.01); G01N 2333/525 (2013.01); G01N 2333/5421 (2013.01); G01N 2333/70578 (2013.01);
Abstract

The disclosure provides methods of using biomarkers to improve diagnosis of forms of prostate. The method includes testing a biological sample from an individual for a interleukin-8 (IL-8), Tumor necrosis factor alpha (TNF-a) and soluble tumor necrosis factor-α receptor 1 (sTNFR1), and may further include testing for prostate serum antigen (PSA). Use of these markers in combination provides tests that are more sensitive and specific than PSA in differentiating benign versus malignant prostate disease and/or localized CaP versus metastatic CaP and show that the specificity and sensitivity of a PSA-based CaP diagnosis can be significantly enhanced by measuring IL-8, TNF-a and sTNFR1.


Find Patent Forward Citations

Chadha, Kailash. (2018). Biomarkers for prostate cancer comprising interleukin-8 (il-8), tumor necrosis factor alpha and soluble tumor necrosis factor-alpha receptor 1 (U.S. Patent No. 9995748). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9995748

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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