The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

Mar. 24, 2016
Applicant:

Sysmex Corporation, Kobe-shi, Hyogo, JP;

Inventors:

Rena Tsuruoka, Kobe, JP;

Yukiko Miura, Kobe, JP;

Assignee:

SYSMEX CORPORATION, Kobe-shi, Hyogo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); G01N 33/542 (2006.01); G01N 1/44 (2006.01); G01N 21/64 (2006.01); G01N 21/76 (2006.01);
U.S. Cl.
CPC ...
G01N 33/542 (2013.01); G01N 1/44 (2013.01); G01N 21/6428 (2013.01); G01N 21/763 (2013.01); G01N 2021/6417 (2013.01); G01N 2021/6432 (2013.01); G01N 2021/6441 (2013.01); G01N 2333/76 (2013.01);
Abstract

Disclosed is a method of determining whether a temperature of a sample has reached a predetermined temperature. The method comprises the steps of: mixing an albumin-containing sample with a peptide reagent comprising a peptide for temperature determination; heating the mixture; detecting an optical change of the mixture; and determining whether the temperature of the mixture has reached the predetermined temperature based on the detection result of the optical change. In the method, a dissociation constant (K) of binding of the peptide for temperature determination to albumin is 500 μM or more, and the peptide for temperature determination comprises a first labeling substance and a second labeling substance.


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