The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2018

Filed:

May. 30, 2012
Applicants:

Frank Osterroth, Dietzenbach, DE;

Christoph Uherek, Seligenstadt, DE;

Christoph Bruecher, Eschborn, DE;

Benjamin Daelken, Frankfurt am Main, DE;

André Engling, Frankfurt am Main, DE;

Chantal Zuber, Frankfurt am Main, DE;

Niklas Czeloth, Dreieich, DE;

Holger Wallmeier, Sulzbach, DE;

Kirsten Völp, Karben, DE;

Gregor Schulz, Umkirch, DE;

Inventors:

Frank Osterroth, Dietzenbach, DE;

Christoph Uherek, Seligenstadt, DE;

Christoph Bruecher, Eschborn, DE;

Benjamin Daelken, Frankfurt am Main, DE;

André Engling, Frankfurt am Main, DE;

Chantal Zuber, Frankfurt am Main, DE;

Niklas Czeloth, Dreieich, DE;

Holger Wallmeier, Sulzbach, DE;

Kirsten Völp, Karben, DE;

Gregor Schulz, Umkirch, DE;

Assignee:

BIOTEST AG, Dreieich, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 33/50 (2006.01); C07K 16/28 (2006.01); G06G 7/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/505 (2013.01); C07K 16/2812 (2013.01); C07K 2299/00 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/75 (2013.01); G01N 2333/70514 (2013.01);
Abstract

Provided are methods of screening to identify molecules capable of binding to CD4 and capable of activating CD4+CD25+ regulatory T cells. Further provided are antibodies and antibody fragments capable of activating CD4+CD25+ regulatory T cells and methods and uses involving the antibodies and fragments thereof.


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